Sunday, 3 June 2012

George Zimmerman back in Florida to surrender

George Zimmerman was expected to be back in jail later Sunday afternoon. NBC's Charles Hadlock reports from Sanford, Fla.

By Charles Hadlock, NBC News, and M. Alex Johnson, msnbc.com

George Zimmerman, the man charged with second-degree murder in the shooting death of Florida teenager Trayvon Martin, has returned to Florida to surrender after a judge revoked his bail, Zimmerman's attorney said Sunday.


Charles Hadlock is a correspondent for NBC News. M. Alex Johnson is a reporter for msnbc.com. Follow M. Alex Johnson on Twitter and Facebook.


Zimmerman, 28, arrived in the state Saturday night from an undisclosed "secure location," where he has been staying because of "significant threats against his life," his lawyer, Mark O'Mara, said Sunday. He was expected to be back in the Seminole County jail by midafternoon ET.


Zimmerman, a neighborhood watch captain in Sanford, Fla., was released on $150,000 bail on April 20 after he was charged with killing Martin, 17, who was unarmed, in February. The case divided the country along racial and ethnic lines; Martin was black, while Zimmerman is the son of a white man and a Peruvian woman.

But Seminole County Circuit Judge Kenneth Lester revoked Zimmerman's bond Friday after learning that Zimmerman and his wife may have misled him about their assets when he set bond. Prosecutors demonstrated that Zimmerman had at least $135,000 he didn't disclose in a special PayPal account he had set up to pay for his defense.

By concealing the defense contributions, Zimmerman benefited from a lower bond than he might have been granted had he and his family told the truth about how much money they really had, Lester said.

O'Mara said in a posting on the defense team's website that he would seek a new bond hearing, at which he would argue that "the vast majority" of the donated money was in an independently managed trust and that neither "Mr. Zimmerman or his attorneys have direct access to the money."

Benjamin Crump, an attorney for Martin's family, said Lester's finding that Zimmerman was dishonest is "very important because his credibility is the most important thing in this entire case."

Full coverage of the Trayvon Martin case

But "the defense team hopes that Mr. Zimmerman's voluntary surrender to Sanford police will help demonstrate to the court that he is not a flight risk," O'Mara said.

More content from msnbc.com and NBC News:

Follow US News on msnbc.com on Twitter and Facebook

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Lower Your Car Insurance Rates With These Tips | Cheap Auto ...

If you are 55 or older and have participated in one of these classes, you may be eligible for such a discount. It is great when you receive a 10% discount on car insurance.

Always research anytime your insurance company offers you a warranty on parts that were used to fix your car. Many repair shops will guarantee their work, and auto parts makers will repair any parts they make. Do your research to find out if there is any kind of guarantee, before you spend any money on a warranty that isn?t necessary.

If your car is driven a minimal amount of miles each year, let your insurance company know. It could save you money. Obviously, decreasing the miles you drive annually is a good way to lower your insurance premiums.

Begin by taking an honest look at at the kind of insurance coverage that you actually need. You probably don?t need every insurance coverage option. If you tend to have accidents, you would be wise to pay for collision coverage.

Investigate which discounts are open to you and ensure you capitalize on all of them. You may also save a lot by claiming discounts.

When you buy a new CD player or install any other add-on, keep the receipt as a record for insurance purposes. You?ll need this as proof if your car is stolen or damaged. If you have decided to make expensive modifications, you need to make certain your insurance policy covers them in the case of any damage done or a theft occurs.

If issues with your driving record are raising your insurance premiums, then you may be able to take action to reduce your rate. For instance, some insurance companies will lower your rate after you successfully complete a driving course after experiencing an accident or a ticket. Some companies, like Progressive, offer their customers the option to temporarily add a chip to their car which will monitor their driving habits everyday, and if those habits show responsible driving, they will lower your rate.

Now that you?ve read this article, you should have a better understanding of auto insurance, so you will be more confident when you make decisions about coverage. You should educate yourself on auto insurance so you don?t become confused when different choices come up.

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Saturday, 2 June 2012

Secret donors bankroll UK queen's celebration

Live from London, Meredith Vieira previews Queen Elizabeth II's Diamond Jubilee weekend, including never-before-seen home movies released by Prince Charles. Camilla Tominey and NBC's Ben Fogle chat about the excitement in the air.

?

By Will Fitzgibbon, The Bureau of Investigative Journalism

LONDON -- It will be a weekend of celebration across Britain. Not least among suffering retailers, who amid the country's double-dip recession will be cheering as loudly as the flag-flying crowds lining London's River Thames to mark Queen Elizabeth II's Diamond Jubilee.

But despite the estimated 823 million pounds ($1.25 billion) expected to be spent by revellers this weekend, British businesses have proved stingy when it comes to raising the funds for the piece de resistance: Sunday's advertising-free pageant will include?a three-hour flotilla featuring more than 1,000 boats.


The committee responsible for the event earlier this year tried entice British companies into contributing to its 10.5 million pound ($16 million) cost. But with a?ban on advertising on either the riverside or on participating boats,?it proved to be a difficult sell and organizers had to draw on contributions from foreign companies and individuals to make up the shortfall.

Jubilee fever is gripping the U.K. in the form of royal souvenirs ? but the ultimate Jubilee gift may be a one-of-a-kind desk complete with a hidden diamond, which will be auctioned off for charity. NBC's Ben Fogle reports.

Lord Salisbury, the chairman of?Thames Diamond Jubilee Pageant,?reportedly said that he did not wish to empty the public purse. ?

Instead organizers had to approach a number of non-British companies to pay for the costs, which include 7,000 stewards as well as festivities planned in Battersea Park.

'Six-figure checks'
Official supporters include American oil company Chevron, advertising company AMV BBDO and Boris Johnson, who is London's New York-born mayor. An additional 20 publicly listed donors have contributed to the tab.

Read more stories from The Bureau of Investigative Journalism

Companies from America, Australia and the Far East have reportedly signed "six-figure checks" as contributions.

However, the British public will never know the full list of organizations that contributed to the funding as the Jubilee Foundation only lists the donors who wish to be named.

While more than a century separates festivities marking Queen Elizabeth II's 60 years on the throne from those honoring her predecessor Queen Victoria, surprising similarities connect the commemorations. NBC News' Jim Maceda reports.

Among this list there are 14 U.K. individuals and companies and six foreign individuals and businesses. This list includes American banking giants Goldman Sachs and JP Morgan and Japanese brokering house Nomura Group.

According to a Thames Diamond Jubilee Pageant spokeswoman, there are "a considerable number of contributors who have made donations and do not wish to be named."

More Diamond Jubilee coverage from Britain's ITV News

Other events, where companies are allowed to market themselves, have proved more popular to companies.

With just days to go until the country's largest river event in 350 years, a complex security operation has kicked in to ensure the safety of the thousand boats that will accompany the Queen down the Thames for the Jubilee river pageant. The flotilla will include sailing ships, music barges and a Hawaiian war canoe. ITN's Fatima Manji reports.

The biggest commercial boon will be the Queen's Jubilee Picnic, to be held in the gardens of Buckingham Palace on Monday and attended by 13,000 guests.?

Supermarket giant Waitrose may be providing 10,000 free hampers for the Jubilee Picnic but its commercial gains are already pouring in.

Waitrose has predicted its strawberry sales will increase seven-fold and "sales of Elderflower cordial have been soaring by an incredible 1,000 percent."

London is getting dressed up for the Jubilee weekend .. hanging out the bunting for the Queen's procession. In the royal mews at Buckingham Palace they're preparing for a second grand royal occasion in just over a year. The carriage that will take the Queen and Prince Philip back after a service at St Paul's Cathedral s being polished up again. ITN's Tim Ewart reports.?

A survey by Moneysupermarket.com also suggests Britons will spend 823 million pounds ($1.26 billion), or an average of 40 pounds ($61) per person on Jubilee-related purchases.

However, not everything is in the best possible taste. Diamond Jubilee sick bags are among the items being sold.

Also from The Bureau of Investigative Journalism:

?

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Transit of Venus 2012 App Enables Cosmic Calculations Next Week

[ [ [['Connery is an experienced stuntman', 2]], 'http://yhoo.it/KeQd0p', '[Slideshow: See photos taken on the way down]', ' ', '630', ' ', ' ', ], [ [['Connery is an experienced stuntman', 7]], ' http://yhoo.it/KpUoHO', '[Slideshow: Death-defying daredevils]', ' ', '630', ' ', ' ', ], [ [['know that we have confidence in', 3]], 'http://yhoo.it/LqYjAX ', '[Related: The Secret Service guide to Cartagena]', ' ', '630', ' ', ' ', ], [ [['We picked up this other dog and', 5]], 'http://yhoo.it/JUSxvi', '[Related: 8 common dog fears, how to calm them]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 5]], 'http://bit.ly/JnoJYN', '[Related: Did WH share raid details with filmmakers?]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 3]], 'http://bit.ly/KoKiqJ', '[Factbox: AQAP, al-Qaeda in Yemen]', ' ', '630', ' ', ' ', ], [ [['have my contacts on or glasses', 3]], 'http://abcn.ws/KTE5AZ', '[Related: Should the murder charge be dropped?]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 5]], 'http://yhoo.it/JD7nlD', '[Related: Bristol Palin reality show debuts June 19]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 1]], 'http://bit.ly/JRPFRO', '[Related: McCain adviser who vetted Palin weighs in on VP race]', ' ', '630', ' ', ' ', ], [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['the 28-year-old neighborhood watchman who shot and killed', 15]], 'http://news.yahoo.com/photos/white-house-stays-out-of-teen-s-killing-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120411/martinzimmermen.jpg', '630', ' ', 'AP', ], [ [['Titanic', 7]], 'http://news.yahoo.com/titanic-anniversary/', ' ', 'http://l.yimg.com/a/p/us/news/editorial/b/4e/b4e5ad9f00b5dfeeec2226d53e173569.jpeg', '550', ' ', ' ', ], [ [['He was in shock and still strapped to his seat', 6]], 'http://news.yahoo.com/photos/navy-jet-crashes-in-virginia-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120406/jet_ap.jpg', '630', ' ', 'AP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]

[ [ [['did not go as far his colleague', 8]], '29438204', '0' ], [ [[' the 28-year-old neighborhood watchman who shot and killed', 4]], '28924649', '0' ], [ [['because I know God protects me', 14], ['Brian Snow was at a nearby credit union', 5]], '28811216', '0' ], [ [['The state news agency RIA-Novosti quoted Rosaviatsiya', 6]], '28805461', '0' ], [ [['measure all but certain to fail in the face of bipartisan', 4]], '28771014', '0' ], [ [['matter what you do in this case', 5]], '28759848', '0' ], [ [['presume laws are constitutional', 7]], '28747556', '0' ], [ [['has destroyed 15 to 25 houses', 7]], '28744868', '0' ], [ [['short answer is yes', 7]], '28746030', '0' ], [ [['opportunity to tell the real story', 7]], '28731764', '0' ], [ [['entirely respectable way to put off the searing constitutional controversy', 7]], '28723797', '0' ], [ [['point of my campaign is that big ideas matter', 9]], '28712293', '0' ], [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]

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UCLA football scholarship for 'Diddy' Combs' son

(AP) ? Justin Combs, the 18-year-old son of hip-hop mogul Sean "Diddy" Combs, will attend UCLA on a $54,000 football scholarship.

It is one of 285 athletic scholarships the university hands out every year.

It comes at a time when student fees are rising and a year after the university had to use more than $2 million in student fees to cover an athletic department funding gap.

Money for Combs' scholarship will not affect need-based scholarships awarded by the university, UCLA spokesman Ricardo Vazquez told the Los Angeles Times.

"There is a big separation between financial aid based on need and how that's funded and how athletic scholarships are funded and awarded to students," he said, noting that athletic scholarships come from athletic department ticket sales, corporate partnerships, media contracts and private donations.

The newspaper said Justin Combs defended taking the scholarship on Twitter: "Regardless what the circumstances are, I put that work in!!!! ... PERIOD."

The senior Combs is worth an estimated $475 million and gave his son a $360,000 Maybach car for his 16th birthday, the Times said.

Justin Combs, a 5-foot-9, 170-pound defensive back, graduated from New Rochelle Iona Prep in New York with a 3.75 grade point average. He also had scholarship offers from Illinois, Virginia and Wyoming.

If needy students are unaffected, there is no problem, said Emily Resnick, outgoing president of UCLA's Undergraduate Students Association. "If his athletic abilities deserve it, then more power to him."

Joelle Gamble, who will graduate from the university in a few weeks, said the scholarship could be considered an investment since UCLA would probably benefit by the celebrity Combs could bring to the school.

"It's how college athletics works. This is how we're going to get money," she said.

A few years ago, former Southern California basketball coach Tim Floyd said fame was a factor when he offered a scholarship to rapper Master P's son, Romeo, for the 2008-2009 season. But Romeo left the team in 2010 after playing just 19 minutes in two seasons as a Trojan.

___

Information from: Los Angeles Times, http://www.latimes.com

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Friday, 1 June 2012

Business-Focused Ad Startup Bizo Launches Self-Serve Retargeting

bizo logoStartup Bizo tries to help advertisers reach a business audience using methods like retargeting. Now it's making those retargeting capabilities available in a self-serve product. For anyone who needs a refresher on the nomenclature, if you visit a website but failed to sign up or buy anything, then see ads for that company following you around the Web ? well, you can thank retargeting. (As someone who has to visit startup websites as part of his job, this has become a constant annoyance.) However, Bizo says it uses retargeting in virtually all of its display advertising campaigns, because it works ??it's going after people who have already expressed interest in a product or service, and it helps businesses stay at the top-of-mind for those consumers.

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Researchers identify promising biomarkers and new therapeutic targets for kidney cancer

Researchers identify promising biomarkers and new therapeutic targets for kidney cancer [ Back to EurekAlert! ] Public release date: 31-May-2012
[ | E-mail | Share Share ]

Contact: Dorsey Griffith
dorsey.griffith@ucdmc.ucdavis.edu
916-734-9118
University of California - Davis Health System

(SACRAMENTO, Calif.) Using blood, urine and tissue analysis of a unique mouse model, a team led by UC Davis researchers has identified several proteins as diagnostic biomarkers and potential therapeutic targets for kidney cancer. Subject to follow-up validation testing, inhibition of these proteins and several related pathways holds promise as a form of therapy to slow the growth of kidney tumors.

In a paper just published online in the journal Cancer Research, the researchers found high concentrations of specific proteins that point to alterations in three sequences of chemical reactions known as biochemical pathways of mice implanted with human kidney cancer cells. The findings suggest that cancerous tumors modulate the pathways, which in turn makes these pathways potential therapeutic targets.

Nicotinamide and cinnamoylglycine, which were altered as a signature of one of the pathways, are just two of approximately 2,000 chemicals, or metabolites, that the human body produces. Metabolites, referring to any substance produced by metabolism, are a reflection of the body's processes in real time. The field of study, known as metabolomics, enables researchers to discover biomarkers and to identify novel therapeutic targets.

The study used metabolomics techniques and instrumentation to simultaneously examine chemicals in two biofluids (urine and serum, or blood) as well as tissue from kidney cancer mice models. Seeking to describe the utility of these fluids as tumor indicators, they found that serum metabolomics analysis is the most accurate proxy of chemical changes that are related to kidney cancer.

"It's exciting to report that our identification of several important metabolic processes may well result in the discovery of diagnostic markers and new therapeutic targets for kidney cancers," said lead author Robert H. Weiss, a professor in the UC Davis Division of Nephrology, Department of Internal Medicine. Currently, there are no tests to easily identify kidney cancer and current treatments are not always successful, so these markers will be important tools for detection and new treatments of the disease.

For the study, researchers transplanted human kidney cancer cells into a mouse model capable of growing human tumors. Researchers compared the metabolites identified in the implanted mice against those in a control group of mice that had surgery, but no cancer cells implanted.

If further research with mouse models demonstrates that inhibition of the newly identified targets works in therapy, then preparation for human trials will be a next step.

"This research represents collaboration among many kinds of experts, all of whom are concerned that kidney cancer patients have too few treatment options, which often have debilitating side effects," said Weiss, who serves as chief of nephrology at the Sacramento Veterans' Administration Medical Center in addition to his work at UC Davis.

###

The research was funded by the National Institutes of Health and the Medical Service of the U.S. Department of Veterans' Affairs, grants 1R01CA135401-01A1 and 1R01DK082690-01A1. Other UC Davis authors were Sheila Ganti and Omran Abu Aboud of the Department of Internal Medicine, Sandra L. Taylor and Kyoungmi Kim of the Department of Public Health Sciences, Joy Yang of the Department of Urology, and Christopher Evans of the Comprehensive Cancer Center and Department of Urology. Authors also included Michael V. Osier of the Rochester Institute of Technology and Danny C. Alexander of Metabolon in Durham, N.C.

UC Davis Comprehensive Cancer Center is the only National Cancer Institute-designated center serving the Central Valley and inland Northern California, a region of more than 6 million people. Its specialists provide compassionate, comprehensive care for more than 9,000 adults and children every year, and access to more than 150 clinical trials at any given time. Its innovative research program engages more than 280 scientists at UC Davis, Lawrence Livermore National Laboratory and Jackson Laboratory (JAX West), whose scientific partnerships advance discovery of new tools to diagnose and treat cancer. Through the Cancer Care Network, UC Davis collaborates with a number of hospitals and clinical centers throughout the Central Valley and Northern California regions to offer the latest cancer care. Its community-based outreach and education programs address disparities in cancer outcomes across diverse populations. For more information, visit cancer.ucdavis.edu.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Researchers identify promising biomarkers and new therapeutic targets for kidney cancer [ Back to EurekAlert! ] Public release date: 31-May-2012
[ | E-mail | Share Share ]

Contact: Dorsey Griffith
dorsey.griffith@ucdmc.ucdavis.edu
916-734-9118
University of California - Davis Health System

(SACRAMENTO, Calif.) Using blood, urine and tissue analysis of a unique mouse model, a team led by UC Davis researchers has identified several proteins as diagnostic biomarkers and potential therapeutic targets for kidney cancer. Subject to follow-up validation testing, inhibition of these proteins and several related pathways holds promise as a form of therapy to slow the growth of kidney tumors.

In a paper just published online in the journal Cancer Research, the researchers found high concentrations of specific proteins that point to alterations in three sequences of chemical reactions known as biochemical pathways of mice implanted with human kidney cancer cells. The findings suggest that cancerous tumors modulate the pathways, which in turn makes these pathways potential therapeutic targets.

Nicotinamide and cinnamoylglycine, which were altered as a signature of one of the pathways, are just two of approximately 2,000 chemicals, or metabolites, that the human body produces. Metabolites, referring to any substance produced by metabolism, are a reflection of the body's processes in real time. The field of study, known as metabolomics, enables researchers to discover biomarkers and to identify novel therapeutic targets.

The study used metabolomics techniques and instrumentation to simultaneously examine chemicals in two biofluids (urine and serum, or blood) as well as tissue from kidney cancer mice models. Seeking to describe the utility of these fluids as tumor indicators, they found that serum metabolomics analysis is the most accurate proxy of chemical changes that are related to kidney cancer.

"It's exciting to report that our identification of several important metabolic processes may well result in the discovery of diagnostic markers and new therapeutic targets for kidney cancers," said lead author Robert H. Weiss, a professor in the UC Davis Division of Nephrology, Department of Internal Medicine. Currently, there are no tests to easily identify kidney cancer and current treatments are not always successful, so these markers will be important tools for detection and new treatments of the disease.

For the study, researchers transplanted human kidney cancer cells into a mouse model capable of growing human tumors. Researchers compared the metabolites identified in the implanted mice against those in a control group of mice that had surgery, but no cancer cells implanted.

If further research with mouse models demonstrates that inhibition of the newly identified targets works in therapy, then preparation for human trials will be a next step.

"This research represents collaboration among many kinds of experts, all of whom are concerned that kidney cancer patients have too few treatment options, which often have debilitating side effects," said Weiss, who serves as chief of nephrology at the Sacramento Veterans' Administration Medical Center in addition to his work at UC Davis.

###

The research was funded by the National Institutes of Health and the Medical Service of the U.S. Department of Veterans' Affairs, grants 1R01CA135401-01A1 and 1R01DK082690-01A1. Other UC Davis authors were Sheila Ganti and Omran Abu Aboud of the Department of Internal Medicine, Sandra L. Taylor and Kyoungmi Kim of the Department of Public Health Sciences, Joy Yang of the Department of Urology, and Christopher Evans of the Comprehensive Cancer Center and Department of Urology. Authors also included Michael V. Osier of the Rochester Institute of Technology and Danny C. Alexander of Metabolon in Durham, N.C.

UC Davis Comprehensive Cancer Center is the only National Cancer Institute-designated center serving the Central Valley and inland Northern California, a region of more than 6 million people. Its specialists provide compassionate, comprehensive care for more than 9,000 adults and children every year, and access to more than 150 clinical trials at any given time. Its innovative research program engages more than 280 scientists at UC Davis, Lawrence Livermore National Laboratory and Jackson Laboratory (JAX West), whose scientific partnerships advance discovery of new tools to diagnose and treat cancer. Through the Cancer Care Network, UC Davis collaborates with a number of hospitals and clinical centers throughout the Central Valley and Northern California regions to offer the latest cancer care. Its community-based outreach and education programs address disparities in cancer outcomes across diverse populations. For more information, visit cancer.ucdavis.edu.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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